Actin-mediated bacterial propulsion: comet profile, velocity pulsations
نویسندگان
چکیده
منابع مشابه
Continuum model of actin-mediated bacterial propulsion
The mechanism of propulsion of host bacteria under the action of actin gel networks is examined by means of a continuum model of the dynamics of the F-actin concentration. The model includes the elasticity of the network, its attachment to the host and the polymerization at the interface with it. A formula for the cruise velocity is derived wherefrom the respective contributions of elasticity a...
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Cells have structure and the ability to move, thanks in part to the actin cytoskeleton, a dynamic cellular scaffolding that facilitates many cellular processes. Actin is mostly concentrated near the outer membrane of the cell, where it is involved in such processes as the formation of membrane protrusions at the leading edges of migrating cells, the movement of certain intracellular vesicles su...
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The Arp2/3 complex consists of seven highly conserved and tightly associated subunits, two of which are the actin-related proteins Arp2 and Arp3. One of the best-studied functions of the Arp2/3 complex is to stimulate actin nucleation and force production at the leading edge of motile cells. What is now clear is that Arp2/3-complex-mediated force production drives many intracellular movements, ...
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Polymerization of actin filaments is necessary for both protrusion of the leading edge of crawling cells and propulsion of certain intracellular pathogens, and it is sufficient for generating force for bacterial motility in vitro. Motile intracellular pathogens are associated with actin-rich comet tails containing many of the same molecular components present in lamellipodia, and this suggests ...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2008
ISSN: 1478-3975
DOI: 10.1088/1478-3975/5/2/026002